![]() Since the launch of oral acute CGRP agents, the performance of injectable CGRP (inhibitors) is now negligible to flat,” Vlad Coric, MD, CEO of Biohaven Pharmaceuticals, said in a statement to PNN. The dual-therapy action of Nurtec ODT is unique and provides clear advantages to both treat and prevent migraine attacks. "This new head-to-head trial affirms that Nurtec ODT is perceived as the new standard of care. Since it was introduced last year, Nurtec has generated about $200 million in revenue for Biohaven, with over 750,000 prescriptions filled. ![]() Therefore, we look forward to sharing the findings from our Emgality versus Nurtec ODT head-to-head trial,” said Anne White, senior vice president of Eli Lilly and president of Lilly Neuroscience.īiohaven’s CEO welcomes the study and sees it as an affirmation of Nurtec’s growing share of the market. “We believe patients should expect more and get more from medications that can help prevent migraine. It’s exciting that insights generated in this first-of-its-kind head-to-head trial will be able to spark treatment plan discussions between people with migraine and their health care providers,” Shivang Joshi, MD, a trial investigator at Dent Neurologic Institute, said in a Lilly press release. ![]() “Lilly’s CHALLENGE-MIG study will help us understand how different types of preventive medications may help people achieve the goals that matter most to them. The so-called CHALLENGE-MIG study will directly compare the efficacy and safety of the two drugs. The company is enrolling 700 adults with episodic migraine in a randomized, double-blind, placebo-controlled trial. ![]() Lilly is now taking the competition a step further, with an unusual head-to-head clinical study – rare in the pharmaceutical industry – that pits Emgality against Nurtec. Eli Lilly hired Olympic athletes to pitch Emgality, an injectable migraine preventative, while reality star Khloé Kardashian is appearing in commercials for Nurtec, an oral medication made by Biohaven Pharamceuticals You’ve probably seen their TV commercials. Costs to patients will vary, depending on insurance coverage, copay assistance programs and rebates.Ĭompetition has grown intense between pharmaceutical companies in the $2 billion U.S. The listed cash price for Emgality is $679 for a single injection or $8,148 annually while 8 tablets of Nurtec cost $1,011 or about $23,000 a year. They are also expensive, whether taken by pill or injection. ![]() “We are confident in the efficacy and tolerability profile of Nurtec ODT as demonstrated in the clinical trials and the well-established patient preference for oral agents over injectables.įirst approved by the FDA in 2018, CGRP inhibitors are the biggest innovation in migraine treatment in decades. It offers flexibility to patients in treating their migraines and is the leading prescribed oral CGRP receptor antagonist,” Pfizer said in a statement. “Nurtec ODT is the first and only medication approved as both an acute treatment for migraine and a preventive treatment for episodic migraine in adults. "Reducing the frequency of migraine headache days can help people experience more freedom from the burden of this debilitating neurological disease and get back to participating in the daily activities that matter most to them."įinal result from the CHALLENGE-MIG trial won’t be posted until later this year. "These results bolster our knowledge of Emgality's ability to work quickly and help patients improve their quality of life with less frequent dosing," Anne White, executive vice president of Eli Lilly, said in a press release. ![]()
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